Application of bupivacaine liposomal pericapsular nerve group block in preoperative analgesia in patients with hip fracture

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300072939

Enrollment

Unknown

Registered

2023-06-28

Start date

2023-07-01

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative analgesia in patients with hip fracture

Interventions

Experimental group:After admission, the patient was injected with 266 mg/20 mL suspension with bupivacaine liposome on the affected side and underwent ultrasound-guided pericystic nerve block.

Control group:After admission, the patient received 20 mL 0.4% ropivacaine injection on the affected side and underwent ultrasound-guided pericystic nerve block

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with hip fracture who was admitted to the trauma department of our hospital; 2.18 kg/m2 = 4 in emergency assessment; 4. Diagnosed with hip fracture (femoral neck fracture, intertrochanteric fracture, intertrochanteric fracture).

Exclusion criteria

Exclusion criteria: 1. Those who do not understand the test method or refuse the test; 2. Allergic to any drug ingredient; 3. Patients who had used pain treatment drugs within 24h before admission; 4. There are PENG or NSAIDs, opioid contraindications; 5. A history of mental illness (schizophrenia, mania, bipolar disorder, insanity, etc.) and long-term use of psychiatric drugs; 6. Patients with cognitive dysfunction: After admission, all patients were evaluated by mini-mentalstate examination (MMSE)(maximum score: 30; scores between 27 and 30 were normal; scores < 27 were cognitive dysfunction). Patients with MMSE score < 24 were evaluated; 7. After completing the basic laboratory examination, the anesthesiology research group physicians assessed the patients with surgical anesthesia contraindications.

Design outcomes

Primary

Measure	Time frame
Visual analogue score (VAS) during rest;Visual analogue score (VAS);Visual analogue score (VAS);	—

Secondary

Measure	Time frame
Sleep quality assessment;The satisfaction degrees of patients;vital signs;complication;	—

Countries

China

Contacts

Public ContactPeng Haobin

Shunde Hospital of Guangzhou University of Chinese Medicine

476736369@qq.com+86 188 1871 1784

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026