Pre-diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 40-59 years old ; 2 Conforming to the diagnostic criteria of prediabetes ; 3 No contraindications to plate test ; 4 Non-vegetarians ; 5 Agree to join this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1 pregnant or lactating women ; 2 patients with hypertension, coronary heart disease, cerebral infarction and other cardiovascular diseases ; 3 patients with emphysema, asthma, chronic obstructive pulmonary disease and other lung diseases ; 4 patients with renal insufficiency, acute and chronic nephritis and other kidney diseases ; 5 patients who received contraceptives, glucocorticoids, lipid-lowering drugs, metformin and other drugs affecting glucose metabolism ; 6 patients who received antibiotics, chemotherapy drugs, probiotics, whole bowel, glutamine and other drugs that affect the intestinal flora ; 7 Smokers and alcoholics ; 8 Patients who exercised regularly for more than 1 hour per week within 3 months before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intestinal microbiota and its metabolites;maximum oxygen uptake;maximum voluntary ventilation;forced vital capacity;FEV1/FVC;forced expiratory volume in the first second; | — |
Secondary
| Measure | Time frame |
|---|---|
| fasting blood glucose;2 hours' postprandial blood glucose;glycosylated hemoglobin;total cholesterol;triglyceride;high density lipoprotein cholesterol;low density lipoprotein cholesterol;ApoA1;ApoB;lipoprotein (a);Lipoprotein-associated phospholipaseA2 (Lp-PLA2);body fat percentage; | — |
Countries
China
Contacts
The Second People's Affiliated Hospital of Fujian University of Traditional Chinese Medicine