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Effect of different sensory and motor training patterns on sensory-motor cortex excitability

Effect of different sensory and motor training patterns on sensory-motor cortex excitability

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072924
Enrollment
Unknown
Registered
2023-06-28
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Non stroke control subjects:N/A
stroke subjects:N/A

Sponsors

Yueyang Hospital of Intergrated Tradition Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for stroke patients 1. Patients diagnosed with supratentorial stroke by clinical evaluation and comprehensive imaging examination meet the diagnostic criteria formulated by the National Cerebrovascular Academic Conference in 2014; 2 Age: 18-80 years old, male or female; 3 Simple intelligent state check (MMSE), 26 points or above; 4 Stroke was confirmed by head CT or MRI, and the duration of the disease was within 2 years. 5 The evaluation and training process ranging from half an hour to an hour can be tolerated; 6 The subject and their legal guardian understood and agreed to participate in the study and jointly signed the informed consent form; 7 Hemiplegia and/or hemiparesis (at least one of the touch, acupuncture and Proprioception disorders was damaged in the assessment) Inclusion criteria for healthy individuals 1. Age range from 18 to 80 years old, regardless of gender; 2. No cognitive or communication barriers 3 The subjects and their Legal guardian understand and agree to participate in the study and jointly sign the informed consent form; 4 No Nervous system disease

Exclusion criteria

Exclusion criteria: 1. Previous epilepsy, brain tumor and other Central nervous system disease; 2. Having aphasia, unilateral neglect, etc., unable to accurately express one's own intentions; 3. Previous limb dysfunction caused by trauma, peripheral neuropathy, etc; 4. Recently ingested or consumed drugs or foods that affect sensory function. 5. Individuals with severe systemic diseases such as heart and lung disease who cannot tolerate rehabilitation treatment; 6 Uncontrolled hypertension, arrhythmia and diabetes complications 7 severe joint contractures (modified Ashworth score = 2 points); 8. Auditory or visual defects may affect training; 9 Use drugs that change the excitability of the Cerebral cortex (antiepileptic drugs, sedative hypnotic drugs, etc.); 10. Obvious pain, Sleep disorder and mental disorder.

Design outcomes

Primary

MeasureTime frame
fNIRS;

Secondary

MeasureTime frame
Fugl Meyer motor function score of affected upper limb;sensory function evaluation;

Countries

China

Contacts

Public ContactWenxi Li

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai

liwenxi2012@126.com+86 159 2104 5260

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026