acute respiratory distress syndrome
Conditions
Interventions
experimental group:prone position vetilation with lung recruitment
control group:prone position
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: ? Age: >18 years old; ? Invasive mechanical ventilation (endotracheal intubation, tracheotomy) was performed for > 24h; ? Oxygenation index (Pa02/Ti02)=150 mmHg, expiratory non-positive pressure (PEEE)=5 cmH20; ? no pneumothorax, intracranial hypertension and other erectile diseases; ? Stable hemodynamics
Exclusion criteria
Exclusion criteria: ? Severe pneumothorax without drainage or continuous air leakage; ? Sternum, rib fracture, spinal injury is not suitable for prone position ventilation; ? unstable Hemodynamics ? Increased intracranial pressure (> 18 mmHg); ? end-stage malignant tumor, chronic disease; ? Abdominal surgery and pregnancy patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU mortality;Length of ICU stay;length of mechanical ventilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-day mortality;IL-6; | — |
Countries
China
Contacts
Public ContactLuo Fengming
West China Hospital of Sichuan University
Outcome results
None listed