Colon cancer
Conditions
Interventions
Immune-fortified group:Oral administration of "suyisu" 400ml per day
Standard nutrition group:Oral administration of "jialichang" 400ml per day
negative control group:Dietary guidance
Sponsors
Changzhou NO.2 People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) It meets the diagnostic criteria for colon cancer in the 2017 Chinese Society of Clinical Oncology (CSCO) guidelines, and is diagnosed by computed tomography (CT) and colonoscopy before surgery, and confirmed by pathological examination after colon cancer after surgery. (2) Patients who have developed distant metastasis or lymph node metastasis, diagnosed with advanced colon cancer, and need to receive at least four cycles of chemotherapy were included in the study. (3) After nutritional risk screening and nutritional assessment, patients with NRS 2002=3 score and PG-SGA score of =4 were included in the study. (4) Karnofsky Functional Status Score (KPS Score) > 50 points. (5) Age= 40 years old, = 80 years old. (6) Life expectancy is at least 6 months.
Exclusion criteria
Exclusion criteria: Gastrointestinal obstruction; Perforation or bleeding of the digestive tract; severe hepatic insufficiency (serum aminotransferases greater than five times normal); severe renal insufficiency (CKD stage 4 and above); severe cardiac insufficiency (NYHA grade 4); severe myelosuppression (myelosuppression grade IV) and/or other conditions deemed clinically unsuitable for inclusion; are receiving thrombolytic or anticoagulant therapy; Allergy to study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma albumin;immunoglobulin; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life; | — |
Countries
china
Contacts
Public ContactShi Li
Changzhou NO.2 People's Hospital
Outcome results
None listed