Cerebral infarction
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Between the ages of 40 and 80; (2) Patients within 48 hours after carotid artery stent angioplasty; (3) Combining with tongue and pulse, it is in line with the syndrome type of pulse obstruction, phlegm and blood stasis obstructing collaterals; (4) Patients with good compliance who agree to participate in the trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) There are clear contraindication to use antiplatelet drugs; (2) Patients with carotid artery dissection; (3) Allergic constitution, such as allergic to two or more drugs or food allergy; (4) Patients with abnormal liver and kidney function or severe elevation of muscle enzymes (ALT, AST>1.5 times the upper normal limit, Cr>the upper normal limit); (5) Patients with severe gastrointestinal diseases such as gastric and duodenal ulcers and perforation, which affect drug absorption; (6) Have serious primary heart, liver, lung, kidney, blood or serious diseases affecting their survival, such as tumor or AIDS; (7) Patients with a history of mental illness or disabilities; (8) According to the judgment of the researcher, other pathological changes that reduce the likelihood of enrollment or complicate enrollment, such as frequent changes in the work environment, may lead to loss of follow-up; (9) Patients participating in clinical observation of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| coverage of stent structs;thickness of neointimal;luminal loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| EPCsEPCs Number of circulating EPCs and functional testing of EPCs after stent placement;EPCs recruitment and differentiation function testing;Severity of poor wall adhesion of the stent; | — |
Countries
China
Contacts
Jiangsu Province Hospital of Traditional Chinese Medicine