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Clinical Study on Mobilizing EPCs with Tongnaoyin to Promote Reendothelialization of Carotid Stents

Clinical Study on Mobilizing EPCs with Tongnaoyin to Promote Reendothelialization of Carotid Stents

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072870
Enrollment
Unknown
Registered
2023-06-27
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral infarction

Interventions

Sponsors

Jiangsu Province Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Between the ages of 40 and 80; (2) Patients within 48 hours after carotid artery stent angioplasty; (3) Combining with tongue and pulse, it is in line with the syndrome type of pulse obstruction, phlegm and blood stasis obstructing collaterals; (4) Patients with good compliance who agree to participate in the trial and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) There are clear contraindication to use antiplatelet drugs; (2) Patients with carotid artery dissection; (3) Allergic constitution, such as allergic to two or more drugs or food allergy; (4) Patients with abnormal liver and kidney function or severe elevation of muscle enzymes (ALT, AST>1.5 times the upper normal limit, Cr>the upper normal limit); (5) Patients with severe gastrointestinal diseases such as gastric and duodenal ulcers and perforation, which affect drug absorption; (6) Have serious primary heart, liver, lung, kidney, blood or serious diseases affecting their survival, such as tumor or AIDS; (7) Patients with a history of mental illness or disabilities; (8) According to the judgment of the researcher, other pathological changes that reduce the likelihood of enrollment or complicate enrollment, such as frequent changes in the work environment, may lead to loss of follow-up; (9) Patients participating in clinical observation of other drugs.

Design outcomes

Primary

MeasureTime frame
coverage of stent structs;thickness of neointimal;luminal loss;

Secondary

MeasureTime frame
EPCsEPCs Number of circulating EPCs and functional testing of EPCs after stent placement;EPCs recruitment and differentiation function testing;Severity of poor wall adhesion of the stent;

Countries

China

Contacts

Public ContactDu Linlin

Jiangsu Province Hospital of Traditional Chinese Medicine

674414031@qq.com+86 159 5191 3783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026