Ovarian cancer
Conditions
Interventions
The routine care group:The routine care group was subjected to a cardiopulmonary exercise test evaluation, one-time individualized exercise prescription, face-to-face evaluation every 3 months, and he
Exercise rehabilitation group:1. a cardiopulmonary exercise test evaluation.
2. A personalized exercise prescription.
3. Patients will be scheduled for a visit and evaluation every three months.
4.
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Any histological subtype of newly diagnosed epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer, suitable for first-line chemotherapy patients; 2.Age range from 18 to 70 years old; 3.The ECOG score is 0-2 points, and the expected life is at least 3 months; 4. Receive first-line chemotherapy after surgery: carboplatin and paclitaxel; 5.Doctors approve participation in moderate intensity exercise; 6.Patients are able to read, write, and understand Chinese; 7.Understanding ability and willingness to sign informed consent form; 8.Patients are willing to undergo two or more venous blood draws for research; 9.For patients who plan chemotherapy or have already started chemotherapy, participants must be enrolled before the start of the second chemotherapy cycle; 10.Normal or slightly abnormal blood routine (white blood cell count=3000 cells)/uL. Absolute neutrophil count=1500cells/uL. Platelet count=70000 cells/uL. Hemoglobin concentration=8.0g/dL), normal or slightly abnormal liver function, and normal or slightly abnormal renal function.
Exclusion criteria
Exclusion criteria: 1.Patients have psychological disorders (hospital anxiety and depression scale=11 points); 2.Patients have a history of surgery, abdominal fistula or gastrointestinal perforation, active bleeding or potential bleeding and had symptomatic CNS metastasis within the first 28 days; 3.Patients have a history of severe liver and kidney dysfunction, uncontrollable blood pressure diabetes; 4.Patients have a history of other cancers and the disease-free period of other cancers was less than 5 years; 5.Patients have a history of severe endocarditis, acute pericarditis, severe aortic valve stenosis, severe lower limb vasculitis or limb dysfunction, acute pulmonary embolism or pulmonary infarction, severe arrhythmia and other diseases; 6.Patients have a history of physical disabilities; 7.Patients have a history of dementia, restlessness, and mental disorder; 8. The patient has a history of Endocarditis, Acute pericarditis, severe Aortic stenosis, severe lower extremity vasculitis or limb dysfunction, acute pulmonary embolism or pulmonary infarction, severe arrhythmia, etc;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival;Life quality of patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall surviva; | — |
Countries
China
Contacts
Public ContactJianwei Zhou
The Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed