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Exploring the protective effect and mechanism of Oligofructose on food allergy after exposure to cephalosporins based on the "Allergic Disease Queue" - a single center, double blind, and randomized controlled study

Exploring the protective effect and mechanism of Oligofructose on food allergy after exposure to cephalosporins based on the "Allergic Disease Queue" - a single center, double blind, and randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072832
Enrollment
Unknown
Registered
2023-06-26
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food allergy

Interventions

control group:none
Oligofructose intervention group:Oral oligofructose solution, 10ml in the morning and 10ml in the evening, lasting for 4 weeks

Sponsors

Affiliated Second Hospital and Yuying Children's Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 2 Years

Inclusion criteria

Inclusion criteria: ? Both parents have resided in Wenzhou for at least 2 years; ? Both parents have no history of infectious diseases such as HIV and other sexually transmitted diseases, and no family hereditary diseases such as Down syndrome; ? Single pregnancy and no maternal complications (pregnancy diabetes, hypertension and eclampsia); ? Both parents agree to participate and are willing to cooperate in the follow-up until the child is 2 years old (sign an informed consent form).

Exclusion criteria

Exclusion criteria: ? Missing baseline clinical data and questionnaire surveys; ? The infant suffers from serious congenital diseases (congenital heart disease, bronchopulmonary dysplasia, biliary atresia, diabetes, etc.); ? Infants and young children have a history of mechanical ventilation.

Design outcomes

Primary

MeasureTime frame
indole;Indole propionic acid;

Countries

Chian

Contacts

Public ContactWeixi Zhang

Affiliated Second Hospital and Yuying Children's Hospital of Wenzhou Medical University

zhangweixi112@163.com+86 138 5772 4836

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026