Sleep disorder
Conditions
Interventions
Dexmedetomidine combined with propofol group:The patient received intraoperative infusion of propofol and dexmedetomidine
Normal saline combined with propofol group:The patient received a saline infusion combined with propofol
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? Sign informed consent; ? Older than 65 years; ? ASA grade II to III; ? Patients who plan to undergo elective thoracic surgery
Exclusion criteria
Exclusion criteria: ? ASA>III; ? Patients with contraindications to regional block technique (allergy to local anesthetic, infection around puncture site and coagulation disorder); ? Have a history of dependence on painkillers; ? Dementia patients or cognitive dysfunction (positive CAM scale, MMSE scale score less than 24 points); ? Any cerebrovascular accident occurred within 3 months, such as stroke, transient ischemic attack (TIA), etc ? Anyone with difficulty in communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Campbell's sleep quality score; | — |
Secondary
| Measure | Time frame |
|---|---|
| the 6-sulfatoxymelatonin concentration;CAM scale evaluation;Mini-mental State Examination score; | — |
Countries
China
Contacts
Public ContactBin Mei
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed