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Effect of enteral eco immunonutrition on patients undergone pancreatoduodenectomy

A randomized controlled trial study on the effect of early enteral eco immunonutrition therapy on the patients undergone pancreaticoduodenectomy.

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072807
Enrollment
Unknown
Registered
2023-06-26
Start date
2020-09-10
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periampullary and pancreatic head cancer

Interventions

Experimental group:early enteral eco immunonutrition therapy
Conrtrol group:Provide nutritional support according to the current clinical situation

Sponsors

The First Affiliated Hospital of Xi’an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Age = 18 years and = 80 years; 2) With Periampullary and pancreatic head cancer who underwent pancreaticoduodenectomy; 3) With NRS 2002 nutritional risk score = 3 points; 4) Without severe hepatic and renal insufficiency; 5)BMI=18.5 Kg/M2 6) With signing informed consent for treatment.

Exclusion criteria

Exclusion criteria: 1) With Signs of allergy or hypersensitivity to soy protein, milk protein and fish protein; 2) With Lactose intolerant; 3) With poor compliance so as to unable to complete the RCT; 4) With severe gastrointestinal dysfunction and risk of intestinal fistula after gastrointestinal surgery; 5) With congenital metabolic dysfunction; 6) With unwilling to participate in the study for any reason.

Design outcomes

Primary

MeasureTime frame
Serum albumin;prealbumin; urea nitrogen; creatinine; lymphocyte count ;postoperative ventilation time;

Secondary

MeasureTime frame
immunoglobulin (IGA, IgG, IgM);

Countries

China

Contacts

Public ContactBinwu Sheng

The First Affiliated Hospital of Xi’an Jiaotong University

bwsheng@126.com+86 29 8532 3463

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026