Postoperative Delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) American Society of Anesthesiology (ASA) physical status (I-IV). (2) Age= 60 years old . (3) Undergo any of the following types of cardiac surgery under elective general anesthesia: coronary artery bypass graft with or without valve surgery (aortic and/or mitral); valve surgery; aortic surgery. (4) The surgical plan is at least 5 days after meeting the inclusion criteria.
Exclusion criteria
Exclusion criteria: (1) History of psychiatric diseases such as Parkinson's disease and Alzheimer's disease . (2) History of alcohol, psychotropic drugs and drug dependence . (3) Communication disorders and inability to understand the contents of the scale . (4) History of brain disease (such as cerebral infarction, cerebral hemorrhage) or recent history of seizures ( 6 years of education) MMSE < 24 . (6) Positive preoperative Confusion Assessment Method test (CAM) . (7) Active depression or as indicated by the Geriatric Depression Scale screening test (score = 10) . (8) involved in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of delirium within 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of delayed neurocognitive recovery (7-30 days);Incidence of postoperative cognitive dysfunction (30 days to 1 year);the time of first onset of delirium and the duration and severity of delirium;Incidence of postoperative depression(GDS score);Postoperative recovery status (PQRS score);Postoperative pain score (NRS score);Extubation time;ICU hospitalization time;total hospitalization time;All-cause mortality at 1 year after surgery; | — |
Countries
China
Contacts
The Affiliated Hospital of Xuzhou Medical University