cancer
Conditions
Interventions
experimental group:cancer related fatigue standard treatment and transcutaneous auricular vagus nerve stimulation
control group:cancer related fatigue standard treatment and sham transcutaneous auricular vagus nerve stimulation
Sponsors
The First Affiliated Hospital of the Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Patients with adjuvant radiotherapy after breast cancer surgery or patients with radical radiotherapy and chemotherapy for esophageal cancer 2) Age= 18 years old 3) ECOG score 0-2 points
Exclusion criteria
Exclusion criteria: 1) Patients with brain organic lesions, peptic ulcers, arrhythmias, cardiac QTc interval > 450ms, bradypnea (respiratory rate less than 10 times per minute) and other patients who are not suitable for vagus nerve stimulation treatment; 2) Those who use anticholinergic and anti-insomnia drugs; 3) Patients with moderate to severe anemia; 4) Patients with thyroid dysfunction; 5) Patients with major depressive disorder and other mental disorders who are currently or have been diagnosed; 6) Those who are participating in or have participated in vagus nerve or transcranial electrical stimulation therapy for less than 3 months; 7) Those who refuse to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients with fatigue scores(BFI) improved or worsened by more than 2 points; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical, emotional, and cognitive dimensions fatigue scores;Anxiety and depression scores;Quality of life scores;Sleep quality score;Inflammatory factors;Lymphopenia; | — |
Countries
China
Contacts
Public ContactZhao Li'na
The First Affiliated Hospital of the Air Force Medical University (Xijing Hospital)
Outcome results
None listed