Parkinson‘s disease
Conditions
Interventions
PD-FOG:During the performance of tasks, simultaneous collection of brain cortical blood flow signals and kinematic data by using near-infrared, surface electromyography, and sensor devices.
PD-nFOG:During the performance of tasks, simultaneous collection of brain cortical blood flow signals and kinematic data by using near-infrared, surface electromyography, and sensor devices.
HC:During the performance of tasks, simultaneous collection of brain cortical blood flow signals and kinematic data by using near-infrared, surface electromyography, and sensor devices.
Sponsors
Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: PD inclusion criteria: 1)Age 55-80 years old;2)Clear diagnosis of Parkinson's disease;3)Willingness to participate in the study during medication off periods;4)If undergoing deep brain stimulation therapy, willingness to participate in the study during stimulation-off periods;5)Ability to independently walk continuously for more than 10 meters during off periods. Healthy control inclusion criteria: Age 55-80 years old.
Exclusion criteria
Exclusion criteria: PD exclusion criteria: 1)Recent fracture within the past six months that affects balance function;2)Neurological disorders or other symptoms unrelated to PD, such as visual impairment or vestibular dysfunction;3)Significant cognitive impairment (MMSE < 24).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cortical activation;sEMG&Kinematic features; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor impairment;Balance ability;freezing of gait questionaire;physical activity level;fall risk ; | — |
Countries
China
Contacts
Public ContactShen Xia
Yangzhi Affiliated Rehabilitation Hospital of Tongji University
Outcome results
None listed