Lumbar Spine Disease with Osteoporosis
Conditions
Interventions
A group:MIS-TLIF plus cement-augmented pedicle screw fixation
B group:TLIF plus cement augmentation
Sponsors
Department of Spinal Surgery, Lianyungang First People's Hospital
Eligibility
Sex/Gender
All
Age
61 Years to 81 Years
Inclusion criteria
Inclusion criteria: ? patients aged = 60 years; ? with low back pain or/and unilateral neurological symptoms with ineffective regular conservative treatment for 3-6 months; ? imaging: radiographs suggest intervertebral foraminal stenosis, lumbar instability, lumbar slippage (I°, II°), CT and MRI suggest changes such as nerve root and spinal cord compression; ? BMD =-2.5 SD; ? with imaging and physical examination suggesting single-segment lesions; ? who signed the medical ethics agreement.
Exclusion criteria
Exclusion criteria: ? patients aged <60 years; ? with imaging findings incompatible with physical examinations; ? with signs or imaging suggestive of =2 segmental lumbar spine lesions, severe scoliosis, or slippage above II°; ? with bilateral neurological symptoms; ? who were unable to receive surgical treatment; ? with severe osteoporosis (BMD =-2.5 SD, with fracture); ? with other spinal diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The visual analogue scale (VAS) ,ODI and JOA scores before surgery, at 3 months, 6 months, and at the final follow-up visit of these two groups.;Fusion device situation;ODI scores;JOA scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraoperative bleeding;Operation Duration;postoperative drainage; | — |
Countries
China
Contacts
Public ContactRujie Qin
Lianyungang First People's Hospital
Outcome results
None listed