A multicentre randomised controlled double-blind study of low gamma (40Hz) transcranial alternating current stimulation (tACS) in combination with iTBS for the treatment of depression

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300072708

Enrollment

Unknown

Registered

2023-06-21

Start date

2023-06-30

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

sham tACS+ iTBS group:sham tACS+ iTBS treatment

tACS+ iTBS group:tACS+ iTBS treatment

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ?meeting the diagnostic criteria for depression in the International Classification of Diseases and Related Health Problems, 10th Revision (ICD-10); ? right-handedness; ?Age 18 to 65 years old, regardless of gender; ?Patients voluntarily participated in this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1: Patients with severe somatic, infectious and immune system disorders 2: Patients with severe neurological disorders, mental retardation or organic brain disease 3: Patients who are pregnant or lactating 4: Patients who have received electroconvulsive therapy within the last 3 months 5: A history of previous seizures 6: Those assessed as unsuitable for rTMS or tACS treatment and those who are unable to complete the relevant index collection

Design outcomes

Primary

Measure	Time frame
Scale evaluation;Neurophysiological evaluation;	—

Countries

China

Contacts

Public ContactDongsheng Zhou

Ningbo Kangning Hospital

wyzhouds@sina.com+86 139 5782 6345

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026