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Study on the factors related to spinal cord injury repair and related regulatory mechanisms

Study on the factors related to spinal cord injury repair and related regulatory mechanisms

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072704
Enrollment
Unknown
Registered
2023-06-21
Start date
2021-08-19
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury

Interventions

Case Group:None

Sponsors

Huashan Hospital, Fudan University, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Case Group ? The clinical symptoms were consistent with space-occupying lesions in the spinal cord, with sensory or motor disorders in the limbs and body ? Spinal cord occupying requires surgical treatment ? The predicted postoperative survival time is more than 3 years ? It is estimated that the degree of intraoperative tumor resection will reach more than 50% ? The longitudinal length of placeholder is within 1-3 vertebral segments ? no other tumor lesions or distant metastatic lesions in the whole body ? Age range from 18 to 60, male and female ? Can understand and sign the informed consent Healthy Group ? There were no clinical symptoms of neurological impairment. ? Healthy, no history of spinal cord injury ? Age between 18 and 60, male and female ? Can understand and sign the informed consent

Exclusion criteria

Exclusion criteria: Case Group ? Long-term preoperative hormone therapy ? Massive bleeding (total blood loss greater than 1000ml) ? Stroke (except systemic embolism) ? there is a tendency to bleed ? Those who participated in other clinical trials in recent 3 months ? Patients with other neoplastic diseases ? Patients with mental and neurological diseases ? some other researchers deemed it inappropriate to participate in the clinical trial Healthy Group ? Suffering from or having previously suffered from diseases related to spinal cord injury. ? Stroke (except systemic embolism) ? Patients with bleeding tendency ? Participants in other clinical trials in the past 3 months ? Patients with other neoplastic diseases ? Patients with mental and neurological diseases ? Situations in which other investigators consider it inappropriate to participate in the clinical trial

Design outcomes

Primary

MeasureTime frame
Japanese Orthopaedic Association Scores score;

Secondary

MeasureTime frame
American Spinal Injury Association score;Neck Disability Index;European myelopathy score;McCormick score;

Countries

China

Contacts

Public ContactShixin Gu

Huashan Hospital, Fudan University, Shanghai, China

gushixin@gushixin.com+86 21 5460 2951

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026