Spinal cord injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Case Group ? The clinical symptoms were consistent with space-occupying lesions in the spinal cord, with sensory or motor disorders in the limbs and body ? Spinal cord occupying requires surgical treatment ? The predicted postoperative survival time is more than 3 years ? It is estimated that the degree of intraoperative tumor resection will reach more than 50% ? The longitudinal length of placeholder is within 1-3 vertebral segments ? no other tumor lesions or distant metastatic lesions in the whole body ? Age range from 18 to 60, male and female ? Can understand and sign the informed consent Healthy Group ? There were no clinical symptoms of neurological impairment. ? Healthy, no history of spinal cord injury ? Age between 18 and 60, male and female ? Can understand and sign the informed consent
Exclusion criteria
Exclusion criteria: Case Group ? Long-term preoperative hormone therapy ? Massive bleeding (total blood loss greater than 1000ml) ? Stroke (except systemic embolism) ? there is a tendency to bleed ? Those who participated in other clinical trials in recent 3 months ? Patients with other neoplastic diseases ? Patients with mental and neurological diseases ? some other researchers deemed it inappropriate to participate in the clinical trial Healthy Group ? Suffering from or having previously suffered from diseases related to spinal cord injury. ? Stroke (except systemic embolism) ? Patients with bleeding tendency ? Participants in other clinical trials in the past 3 months ? Patients with other neoplastic diseases ? Patients with mental and neurological diseases ? Situations in which other investigators consider it inappropriate to participate in the clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Japanese Orthopaedic Association Scores score; | — |
Secondary
| Measure | Time frame |
|---|---|
| American Spinal Injury Association score;Neck Disability Index;European myelopathy score;McCormick score; | — |
Countries
China
Contacts
Huashan Hospital, Fudan University, Shanghai, China