Bipolar Disorder
Conditions
Interventions
Type I bipolar disorder, manic episode:N/A
Type I bipolar disorder, depressive episode:N/A
Health Control:None
Sponsors
The Affiliated Xuzhou Oriental Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: BD inclusion criteria: a) Gender-neutral, between 18 years = age < 60 years; b) Meeting the diagnostic criteria for type I bipolar disorder in the DSM-V; c) No special diet and no probiotics such as yogurt within 1 week; d) Signed informed consent form. Healthy control group inclusion criteria: a) Any gender, between 18 years = age < 60 years; b) No special dietary habits and no consumption of probiotics such as yogurt within 1 week; Sign the informed consent form.
Exclusion criteria
Exclusion criteria: BD exclusion criteria: a) meeting diagnostic criteria for mental disorders other than Type I bipolar disorder in the DSM-V; b)Those with severe physical illness, substance dependence and neurological disorders; c)Those whose condition, in the opinion of the investigator, affects the safety of the subject (e.g., those with severe suicidal thoughts, behaviors, and severe excitatory arousal); d)antibiotic or antifungal treatment within 1 month prior to admission; e)Alcohol abuse within 30 days prior to the start of the trial or the presence of alcohol or drug dependence within 6 months prior to the trial f)Women during pregnancy or lactation. g)Those who participated in any clinical trial within 30 days prior to baseline. Healthy control exclusion criteria: a)Meeting any diagnostic criteria for mental disorders in the DSM-V; b)Those with severe physical illness, substance dependence and neurological disorders; c)Use of antibiotic or antifungal treatment 1 month prior to admission; d)Persons with alcohol abuse within 30 days prior to the start of the trial or with alcohol or drug dependence within 6 months prior to the trial e)Women during pregnancy or lactation; f) Those who participated in any clinical trial within 30 days prior to baseline.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolomics;gut microbiota; | — |
Countries
China
Contacts
Public ContactJin Chen
The Affiliated Xuzhou Oriental Hospital of Xuzhou Medical University
Outcome results
None listed