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Differential Neural Networks in Type 2 Diabetes Patients with Depression and Cognitive Impairment

Differential Neural Networks in Type 2 Diabetes Patients with Depression and Cognitive Impairment

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072696
Enrollment
Unknown
Registered
2023-06-21
Start date
2023-04-07
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

type 2 diabetes:none
healthy control:none

Sponsors

Zhongda Hospital Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: T2DM Inclusion Criteria: (1) Age 18-65 years old; (2) At least junior high school education; (3) Type 2 diabetes mellitus meeting the 2019 WHO diagnostic criteria; (4) Absence of internal pacemakers or metallic materials, eligible for MRI examination; (5) Right-handed; (6) Informed consent signed by the patient or their legal guardian. HC Inclusion Criteria: (1) Age, gender, and education level matching the patient group; (2) No history of diabetes, no severe cardiac, cerebral, or renal diseases, no history of alcohol or drug abuse, and no family history of mental disorders; (3) Absence of internal pacemakers or metallic materials, eligible for MRI examination; (4) Right-handed; (5) Informed consent signed by the patient or their legal guardian.

Exclusion criteria

Exclusion criteria: (1) Dementia (Montreal Cognitive Assessment [MoCA] score <22; Mini-Mental State Examination [MMSE] score: =22 for high school level (including vocational school), =23 for university level (including junior college)); Activities of Daily Living Scale score <100; (2) Concurrent malignant tumors, brain diseases, thyroid dysfunction, other severe physical illnesses, or mental disorders; (3) Abuse or dependence on psychoactive substances, including alcohol, tobacco, or drugs; (4) Pregnant or breastfeeding women; (5) Patients unable to engage in effective interviews due to physical or mental conditions.

Design outcomes

Primary

MeasureTime frame
Differential Neural Networks;Mini-Mental State Examination,,MMSE;Montreal Cognitive Assessment, MoCA;—

Secondary

MeasureTime frame
logical memory test, LMT;verbal fluency test,VFT;Clock Drawing Test, CDT;digital span test, DST;stroop color-word test,SCWT;—

Countries

China

Contacts

Public ContactYonggui Yuan

Zhongda Hospital Southeast University

yygylh2000@sina.com+86 139 1393 9082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026