Labor analgesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Women with the following characteristics were recruited: healthy, term, nulliparous American Society of Anesthesiologists physical status class II; aged 20–40 years; singleton pregnancies, vertex presentation, in labor; regular uterine contractions at least every 5 min with progressive cervical dilation; requesting epidural analgesia with 2–5 cm cervical dilation; and reporting a baseline pain score =5 on a numerical rating scale (NRS), which evaluates pain from 0–10 (0, no pain; 10, worst imaginable pain).
Exclusion criteria
Exclusion criteria: Exclusion criteria were as follows: body mass index (BMI) >40 kg/m2; cardiac and brain dysfunctions; intrahepatic cholestasis of pregnancy, preeclampsia, and history of substance use disorder; receiving pharmacological analgesics within 4 h of request for epidural analgesia; contraindicated for epidural block; conditions that increase the risk of cesarean delivery (history of uterine abnomaly or surgery); and fetal abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ropivacaine consumption per hour; | — |
Secondary
| Measure | Time frame |
|---|---|
| number of PCEA boluses;the first time of PCEA;numbers of resuce boluses; | — |
Countries
China
Contacts
Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China