acute appendicitis
Conditions
Interventions
Experimental group:direct vision-endoscopic retrograde appendicitis therapy
Control group:endoscopic retrograde appendicitis therapy
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older; 2. Diagnosis of acute uncomplicated appendicitis by following presentations: (1) Clinical suspicion of acute uncomplicated appendicitis and Alvarado scores above 5; (2) CT scan determines acute uncomplicated appendicitis: Clear visualization of the appendix with a diameter above 6 mm (essential criterion); With or without: 1) peri-appendiceal fat stranding; 2) appendicolith(s); 3) the wall of periappendiceal bowel become thicker (cecum >4 mm, ileum >2 mm); Absence any of the following items of complicated appendicitis: 1) extraluminal air; 2) periappendiceal fluid; 3) disseminated intraperitoneal fluid. 3. Written informed consent obtained from patients or their legal representatives.
Exclusion criteria
Exclusion criteria: 1. Patients with acute uncomplicated appendicitis due to non-appendicolith(s) causes and complex appendicitis with appendiceal perforation, abdominal abscess, acute intestinal obstruction, and acute diffuse peritonitis found preoperatively or intraoperatively; 2. Patients with severe infectious or widespread diseases or concurrent acute abdominal conditions; 3. Patients with contraindications to colonoscopy or endoscopic procedures, e.g. with cardiopulmonary and other insufficiencies to tolerate endoscopy; at high risk of shock or gastrointestinal perforation; with impaired coagulation mechanisms and bleeding tendencies; with long-term steroids;. 4. Any terminal illness with life expectancy less than 6 months; 5. Pregnant women or lactating women; 6. Patients who have difficulty cooperating through comprehensive assessment, such as those who refuse to accept research measures or who have a history of mental illness 7. Patients with laxative and contrast media allergies; 8. Patients with a previous history of inflammatory bowel disease (IBD); 9. Patients who have taken part in other studies that can affect the results of the present study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appendicolith clearance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Technical success rate;Recurrent appendicitis rate;The overall complication rate;Duration of post-treated pain;The decline time of inflammation index;Length of postoperative hospital stay;procedure time;X ray application time;body temperature normalized time; | — |
Countries
China
Contacts
Public ContactXin Yang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed