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Multimodal brain magnetic resonance imaging and peripheral blood neurodevelopment-related proteins in children with autism spectrum disorder

Multimodal brain magnetic resonance imaging and peripheral blood neurodevelopment-related proteins in children with autism spectrum disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072683
Enrollment
Unknown
Registered
2023-06-21
Start date
2023-06-24
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ASD

Interventions

Sponsors

China Rehabilitation Research Center, Beijing Bo'ai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 7 Years

Inclusion criteria

Inclusion criteria: ? The age of 2-7 years old; ? The ASD group was diagnosed by DSM-V; ? The normal control group had no abnormal development before and after birth; (4) No MRI contraindications; ? the guardian gives informed consent and signs informed consent; ? None of the children had taken any drugs (including any psychotropic drugs) at the time of participating in the study.

Exclusion criteria

Exclusion criteria: ? History of organic diseases of the nervous system: chronic epilepsy, encephalitis, meningitis, severe brain trauma, brain surgery; (2) Suffering from serious physical diseases of the heart, liver, kidney, endocrine, blood and other systems or other chronic physical diseases; (3) Acute and chronic medical conditions associated with an unbalanced inflammatory response, such as infection, vaccination in the past 4 weeks, or use of any immunomodulatory drugs (including NSaids and aspirin); (4) Common genetic diseases.

Design outcomes

Primary

MeasureTime frame
brain MRI;serum biomaker;

Secondary

MeasureTime frame
IQ;DQ;

Countries

China

Contacts

Public ContactTong Zhang

School of Rehabilitation, Capital Medical University, China Rehabilitation Research Center, Beijing Bo'ai Hospital

Tommzhang@163.com+86 185 1555 2776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026