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A Prospective Single-center Study Of Contrast-enhanced Ultrasonography In The Diagnosis Of Central Neck Lymph Node Metastasts In Thyroid Carcinoma Using Sonazoid

A Prospective Single-center Study Of Contrast-enhanced Ultrasonography In The Diagnosis Of Central Neck Lymph Node Metastasts In Thyroid Carcinoma Using Sonazoid

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072676
Enrollment
Unknown
Registered
2023-06-21
Start date
2022-11-08
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PTC

Interventions

Gold Standard:postoperative pathological results of central cervical lymph nodes.
Index test:ultrasound and contrast-enhanced ultrasound

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1)newly diagnosed patients with (cT1)thyroid nodules (Bethesda system =V cytology) scheduled for thyroidectomy with central neck dissection. 2)patients who will finish the examination of ultrasound and contrast-enhanced ultrasound in the central neck region in one week. 3)the surgical methods are thyroidectomy with central neck dissection. The lymph nodes in the central neck will be examined histologically according to the subregions. 4)patients who have complete clinical and pathological data.

Exclusion criteria

Exclusion criteria: 1) patients with other types of thyroid cancers or other malignant tumors (other types of thyroid cancer are excluded); 2) patients who had hypertension, coronary heart disease, or were allergic to eggs and were not suitable for CEUS examinations; 3) patients who were pregnant or nursing women.

Design outcomes

Primary

MeasureTime frame
Rate of the detection of US for lymph nodes;Rate of the detection of CEUS for lymph nodes;Diagnostic sensitivity of US for central lymph nodes;Diagnostic sensitivity of CEUS for central lymph nodes;Diagnostic specificity of US for central lymph nodes;Diagnostic specificity of CEUS for central lymph nodes;Diagnostic sensitivity of US for central metastatic lymph nodes;Diagnostic sensitivity of CEUS for central metastatic lymph nodes;Diagnostic specificity of US for central metastatic lymph nodes;Diagnostic specificity of CEUS for central metastatic lymph nodes;

Countries

China

Contacts

Public ContactLiu LZ

Sun Yat-Sen University Cancer Center

liulzh@sysucc.org.cn+86 136 0245 7948

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026