Adolescents with depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.DSM-5 diagnosis of depression (including single episode, recurring episode). 2.Montgomery Depression Rating Scale (MADRS) score =12. 3.Age 12-17 years. 4.Patients with intelligence level in the normal range, normal perception, self-expression ability, can complete the baseline scale assessment. 5.Written informed consent from his or her legal guardian is required.
Exclusion criteria
Exclusion criteria: 1.Other mental disorders that meet DSM-5 diagnostic criteria, including organic mental disorders, mental retardation, autism spectrum disorders, schizophrenia, bipolar disorder, eating disorders, obsessive-compulsive disorder, alcohol dependence, drug dependence/abuse, etc. 2.Patients with illness or emotional instability, current positive suicidal ideation (Montgomery Depression Rating Scale suicide score > 4), severe destructive and aggressive behavior. 3.Severe psychotic symptoms (presence of painful or common hallucinations and/or delusions). 4.Combined with serious physical illness and/or evidence that the patient has clinically significant, uncontrolled or unstable cardiovascular, kidney, liver, gastrointestinal, blood, immune, endocrine, metabolic, or pulmonary disease (as determined by history, clinical laboratory or ECG findings, or physical examination) that increases the risk of intervention or confuses the interpretation of the study results; 5.According to the research group, patients who could not cooperate with the cognitive function examiner or were not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery-Asberg Depression Rating Scale (MADRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| BDI-II (Beck Depression Inventory);behavioral inhibition-activation system scale, BIS-BAS scale;Insomnia Severity Index,ISI;International Physical Activity Questionnaire;Level 5 Likert rating Acceptance questionnaire;Adolescent Self-harm Behavior Questionnaire, ASHBQ; | — |
Countries
China
Contacts
The Affiliated Brain Hospital of Guangzhou Medical University