Chronic atrophic gastritis,Gastric precancerous lesions
Conditions
Interventions
Patients with superficial gastritis:None
Patients with Hp infected gastritis:None
Low risk atrophic gastritis patients:None
High risk patients with Atrophic gastritis:None
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Outpatients and inpatients who met the diagnosis of simple superficial gastritis, superficial gastritis with Hp infection, atrophic gastritis with or without intestinal hyperplasia, and heterogeneous hyperplasia by gastroscopy and pathological examination (2) Age 18-75 years (3) conscious, clear language, reading ability, and unimpeded communication with investigators (4) willing to undergo gastroscopy and immunohistochemical index testing, and sign an informed consent form
Exclusion criteria
Exclusion criteria: (1) Those with a history of gastric ulcers, gastric polyps and gastric surgery (2) Long-term users of NSAID drugs (3) Those suspected of having gastric cancer or other systemic malignant lesions (4) Those with a history of gastric surgery (5) Combination of primary diseases of the heart, cerebrovascular, liver, kidney, hematopoietic system, etc. (6) Mental illness and intellectual and language disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LGR5;TFF2;ß-catenin;Cyclin D1;Ki67;Bax; | — |
Countries
China
Contacts
Public ContactPing Wang
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed