Prostate cancer
Conditions
Interventions
Experimental group:177Lu-PSMA-3Q
Control group:177Lu-PSMA-I&T
Sponsors
Department of Nuclear Medicine, First Medical Center, PLA General Hospital
Eligibility
Sex/Gender
Male
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: ? Age > 40 years old 3.0X109L, platelet count >75X109/L, serum creatinine and major liver enzymes levels are not higher than 2 times and 5 times of the upper limit of normal reference values; ? no urinary tract obstruction;
Exclusion criteria
Exclusion criteria: Exclusion criteria: ? Prior treatment with PSMA targeted radiopharmaceuticals. (2) 18F-PSMA-3Q PET/CT scan results showed negative or positive concentrations greater than 10, or 3 tumors/liver SUV uptake ratio less than 2; ? Biochemical values do not meet the above, or urinary tract obstruction; (4) Plan to have a family plan during the treatment period and the following 6 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SPECT/CT;PSA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone scan; | — |
Countries
China
Contacts
Public ContactJinming Zhang
Department of Nuclear Medicine, First Medical Center, PLA General Hospital
Outcome results
None listed