idiopathic inflammatory myopathy
Conditions
Interventions
idiopathic inflammatory myopathy patients with MDA5 positive antibody:None
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
14 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Meet the Bohan and Peter diagnostic criteria (1975) or the EULAR/ACR diagnostic criteria (2017) for idiopathic inflammatory myopathy; 2.MDA5 positve patients valued by Myositis specific autoantibodies spectrum; 3.Aged >14 years; 4.Patients volunteered to participate in this study, with good compliance, and were able to understand and sign the informed consent before the study.
Exclusion criteria
Exclusion criteria: 1. Complicated with other connective diseases, including systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, etc; 2. Women who were pregnant, breastfeeding or planning to become pregnant during the study period; 3. Treated with plaasma exchange in 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| titer of MDA5;lung CT;Immunological parameters;Myositis Scale score;Pulmonary function parameters; | — |
Countries
China
Contacts
Public ContactDong Lingli
Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed