Residual sleep disturbances in patients remitted from major depressive disorder
Conditions
Interventions
Acupuncture group:Treatment will be performed by licensed acupuncturists who have at least five years of experience in acupuncture. All the acupuncturists will be trained how to locate acupoints, punc
Hwatuo, Suzhou, China) will be used. Acupuncture treatments will consist of 24 sessions with 30-min duration over eight weeks (three sessions per week, ideally every other day). Acupuncture will be di
Fenglong (ST40), Neiting (ST44) and Quchi (LI11) for phlegm heat internal disturbance
Taixi (KI3) and Shuiquan (KI5) for yin deficiency and fire flourishing
Neiguan (PC6) and Zusanli (ST36) for weakness of the heart and spleen
Qiuxu (GB 40) and Neiguan (PC6) for weakness of the qi of the heart and gallbladder. All acupoints are localized according to the WHO Standard Acupuncture Locations.
Medication group:Patients take estazolam 1 mg daily for 8 weeks.
Sponsors
Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Men or women aged 18-70 years; (2) Met Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) criteria for MDD; (3)Taken fixed dose of the same antidepressant at least 12 weeks before the baseline review or during study participation; (4) HAMD-17 scores=17; (5) Insomnia at least 3 nights a week, which lasted for at least three months,PSQI scores=7; (6) ISI scores=15; (7) All subjects must give full informed consent to this project and sign a written informed consent form before being enrolled in this study.
Exclusion criteria
Exclusion criteria: (1) Participants at high risk of suicide; (2) Having a history of schizophrenic, other psychiatric disorders,or bipolar disorder; (3) Having current alcohol abuse or substance related disorder; (4) Women who are pregnant or lactating or planning to be pregnant during the study; (5) Subjects who have inflammation or abscess at the planned acupuncture site on the body; (6) Subjects who have any other serious illness;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index,PSQI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index,ISI;Hamilton Depression Scale,HAMD17;Hamilton Anxiety Scale,HAMA17;SF-36;Adverse events; | — |
Countries
China
Contacts
Public ContactFu Qingnan
Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University
Outcome results
None listed