Thoracoscopic postoperative analgesia
Conditions
Interventions
Group D (acetaminophen mannitol injection) and Group S (flurbiprofen exate injection):Group D: Intravenous infusion of 500 mg acetaminophen mannitol injection before single lung ventilation
Group S (flurbiprofen exate injection):Group S: Intravenous infusion of 50 mg flurbiprofen axidate injection before single lung ventilation.
Sponsors
the First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. 18= age =65 years old, gender is not limited; 2. Elective surgery; 3. ASA score is Level I or Level II; 4. 18 kg/m2 < BMI < 30kg/m2; 5. Clearly understand and voluntarily participate in the study, and have their informed consent signed;
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) Uncontrolled hypertension and diabetes; (2) liver and kidney function exceeds normal value; (3) Patients with mental system diseases and long-term history of taking psychiatric drugs and cognitive impairment; (4) Pregnant or lactating women; (5) People allergic to acetaminophen, opioids, propofol, muscle pine and other drugs; (6) Other circumstances in which the investigator considers it inappropriate to participate in the experiment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;Choking cough;Extubation time;Adverse reactions; | — |
Countries
China
Contacts
Public Contactjinwenjie
Jiangsu Province Hospital
Outcome results
None listed