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Effect of dexmedetomidine combined with lidocaine surface anesthesia under general anesthesia on emergence agitation and postoperative pain in pediatric tonsillectomy

Effect of dexmedetomidine combined with lidocaine surface anesthesia under general anesthesia on emergence agitation and postoperative pain in pediatric tonsillectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072611
Enrollment
Unknown
Registered
2023-06-19
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsil hypertrophy

Interventions

saline group:5ml of physiological saline sprayed on both tonsils
Lidocaine group:A total of 5ml of 2mg/kg 2% lidocaine + saline was sprayed on both tonsils
Dexmedetomidine group:A total of 5ml of 2ug / kg dexmedetomidine + saline was sprayed on both tonsils
Dexmedetomidine combined with lidocaine group:A total of 5ml of 2ug / kg dexmedetomidine + 2mg / kg 2% lidocaine + saline was sprayed on both tonsils

Sponsors

First Affiliated Hospital of Gannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 12 Years

Inclusion criteria

Inclusion criteria: ( 1 ) Children undergoing elective low-temperature plasma bilateral tonsillectomy combined with adenoid ablation ; ( 2 ) Age 4-12 years old, male and female children can, and the American Society of Anesthesiologists ( American Society ) disease classification of physical condition is grade I ; ( 3 ) Guardian signed informed consent.

Exclusion criteria

Exclusion criteria: ( 1 ) Abnormal mental cognition ; ( 2 ) Have a clear history of allergy to the study drug ; ( 3 ) BMI > 24kg /? ; ( 4 ) Severe sinus bradycardia ; ( 5 ) Children with severe preoperative agitation or anxiety ; ( 6 ) Peers with weight over 95 % or less than 5 % ; ( 7 ) Children whose families refused to participate in the clinical trial.

Design outcomes

Primary

MeasureTime frame
heart rate;r-FLACC Score;PEAD;

Secondary

MeasureTime frame
blood loss;Dosage of propofol during operation;Intraoperative dosage of remifentanil;extubation time;PACU residence time;The incidence of perioperative sinus bradycardia;The incidence of nausea and vomiting 24 h after operation was observed.;

Countries

China

Contacts

Public ContactCHEN LI

First Affiliated Hospital of Gannan Medical College

zgx8778@163.com+86 157 2775 2168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026