Helicobacter pylori infection
Conditions
Interventions
Treatment group:Bismuth spray under gastroscope
Control group:Traditional oral medicine
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: a. Positive rapid urease test and/or urea breath test. b. According to the Sixth National Consensus Report on the Management of Helicobacter pylori Infection, it has indications of Hp eradication. Peptic ulcer, whether active or not and with or without a history of complications; Gastric mucosa-associated lymphoid tissue lymphoma; Early gastric cancer underwent endoscopic submucosal dissection or subtotal gastrectomy. Family history of gastric cancer; Plan to take non-steroidal anti-inflammatory drugs for a long time; Hp gastritis; Gastric hyperplastic polyp; Hp-related dyspepsia; Long-term use of proton pump inhibitors; Iron deficiency anemia of unknown origin; Primary immune thrombocytopenia; Vitamin B12 deficiency; Confirmed Hp infection (no countervailing factor for eradication therapy). c. Age 18 to 70 years old. d. No history of bismuth allergy.
Exclusion criteria
Exclusion criteria: a. Patients who had taken antibiotics or bismuth within 4 weeks before treatment, proton pump inhibitors or H2 receptor antagonists within 2 weeks before treatment, and antiplatelet or anticoagulant drugs within 1 week before treatment. b. Patients whose general condition is not acceptable for gastroscopy. c. Patients with severe heart, kidney, lung and liver diseases. d. Known or suspected allergy to the drug. e. Participants in other clinical trials. f. Other conditions that the researchers deem inappropriate for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urea breath test; | — |
Countries
CChina
Contacts
Public ContactLian Tingting
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed