Oral mucositis and radiation dermatitis
Conditions
Interventions
Oral Mucositis Group:Nahao Spray
Radiation dermatitis group:Nahao Spray
Sponsors
Jiangsu Cance Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Oral Mucositis Group Patients are prepared to receive head and neck radiation therapy with or without chemotherapy,patients are over 18 years old, regardless of gender, can clearly describe symptoms, voluntarily participate in this study, sign an informed consent form, and have a quality of life score and functional status score (Karnofsky) greater than 50. Radiation dermatitis group Patients who are preparing to receive head and neck or breast radiation therapy with or without chemotherapy, with a radiation intensity of 40 Gy or more, age greater than 18 years old, regardless of gender, can clearly describe symptoms, voluntarily participate in this study, sign an informed consent form, and have an activity status score (ECOG) of = 2.
Exclusion criteria
Exclusion criteria: Oral Mucositis Group Patients with oral mucosal diseases before starting radiotherapy, and those who are allergic to the test drug or any of its components; Patients who use other mucosal protectors one week before radiotherapy; Patients with liver and kidney dysfunction, neurological or psychiatric abnormalities; Patients with poor compliance. Radiation dermatitis group Patients with severe and uncontrolled organic lesions or infections, patients who use other skin and mucosal protective agents during radiotherapy, patients who are participating in or have participated in similar clinical studies within the past 30 days, and patients who are allergic to any component of the investigational drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of oral mucosal inflammation;Remission rate of radiation dermatitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral mucositis pain score;Quality of life score;Symptom burden of skin damage in the dermatitis group;Oral mucotitis group functional status score;Dermatitis group functional status score; | — |
Countries
China
Contacts
Public ContactDan song
Jiangsu Cancer Hospital
Outcome results
None listed