Glioma
Conditions
Interventions
Index test:Raman analyzer
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old, regardless of gender; 2. Patients who plan to undergo brain lesion tissue resection surgery or have preoperative clinical diagnosis of gliomas and plan to undergo biopsy; 3. Patients with clinical diagnosis of initial solitary gliomas, or initial solitary intracranial masses or initial non occupying lesions that do not exclude gliomas (such as intracranial metastatic lesions, intracranial infectious lesions, intracranial demyelinating lesions, central nervous system lymphoma, etc.), who have not received radiotherapy or chemotherapy in the past based on their medical history; 4. The patient or their guardian can understand the research purpose, demonstrate sufficient compliance with the trial protocol, and sign an informed consent form; 5. It is possible to obtain tissue samples with a length diameter greater than 0.2cm. Patients diagnosed with initial solitary glioma should take core or marginal tissue, while patients diagnosed with initial single intracranial mass or initial non mass lesions but maybe with gliomas should be taken core tissue.
Exclusion criteria
Exclusion criteria: 1. Investigator judge that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Accuracy ;Positive predictive value;Negative predictive value;Kappa coefficient;The Raman analyzer usability evaluation;Time consumption for the Raman analyzer detection;The defect occurrence rate of the Raman analyzer;Adverse Event Incidence Rate;Serious Adverse Event Incidence Rate;Operator adverse events; | — |
Countries
China
Contacts
Public ContactJiang Tao
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed