None listed
Conditions
Interventions
Norepinephrine group:The initial prophylactic infusion of norepinephrine was administered to the first patient at a rate of 0.05 µg/kg/min, with incremental adjustments (0.01 µg/kg/min) made for subse
Phenylephrine group:The initial prophylactic infusion of phenylephrine was administered to the first patient at a rate of 0.5 µg/kg/min, with incremental adjustments (0.1 µg/kg/min) made for subsequen
Sponsors
The Fifth People's Hospital of Huaian
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: ASA grade II-III singleton patients with preeclampsia undergoing cesarean section under spinal anesthesia
Exclusion criteria
Exclusion criteria: Spinal anesthesia is contraindicated; chronic hypertension, other cardiovascular and cerebrovascular diseases, eclampsia, and severe fetal distress are also contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effective dose (ED) 90 and relative potency ratio of norepinephrine and phenylephrine for preventing post-spinal hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events;Apgar scores;Blood gas analysis of umbilical artery; | — |
Countries
China
Contacts
Public ContactXiangsheng Xiong
The Fifth People's Hospital of Huaian
Outcome results
None listed