post-stroke depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inpatients with a confirmed diagnosis of ischaemic stroke (CIS) by cranial CT or MRI; first episode; duration of illness 3 months to 1 year; at least 2 post-stroke functional deficits; age 20-75 years; meeting the Chinese Classification and Diagnostic Criteria of Mental Disorders, 3rd edition (CCMD-3), Diagnostic and Statistical Manual of Mental Disorders (DSM-V), diagnosed by a specialist psychiatrist as PSD; Hamilton HAMD-17 scale score of 7 to 24 (mild to moderate depression); normal cognition and able to cooperate in completing the assessment scale; no history of serious heart, liver or kidney disease and history of epilepsy, glaucoma and psychosis or medication use; those who voluntarily participated in the study, signed the informed consent form and passed the hospital ethics committee.
Exclusion criteria
Exclusion criteria: People with aphasia and severe cognitive impairment who are unable to cooperate with the examination; combined history of psychiatric disorders such as depression, bipolar disorder, mania; history of alcoholism, epilepsy, post-traumatic stress; unstable vital signs or combined with other serious underlying illnesses; patients with multiple strokes; HAMD-17 total score = 25 or suicidal or self-harming tendencies; participants in other clinical trial studies in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression Symptoms Quick Self-Rating Scale (QIDS-SR16); | — |
Countries
China
Contacts
Yancheng Third People 's Hospital