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The Assessment of PlasmA CircRNA OGDH Levels on Clinical Outcomes in Acute Ischemic StRoke PAtients: A Prospective Cohort Study (PANDORA)

The Assessment of PlasmA CircRNA OGDH Levels on Clinical Outcomes in Acute Ischemic StRoke PAtients: A Prospective Cohort Study (PANDORA)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072569
Enrollment
Unknown
Registered
2023-06-16
Start date
2021-10-18
Completion date
Unknown
Last updated
2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Control group:none

Sponsors

The First Affiliated Hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Age>18 years old 2) Patients diagnosed with AIS within 24 hours of onset who were confirmed by CT/MRI based on Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association 3) Informed consent was signed by the patient or their agent.

Exclusion criteria

Exclusion criteria: 1) The modified Rankin Scale (mRS) score of pre-admission >=2 points 1) Patients with moderate to severe mental disorders or dementia affecting neurological function assessment 3) Patients experienced surgical history within 3 months, and those who had severe acute or chronic infections, autoimmune diseases, and malignant tumors 4) Pregnant or breastfeeding women 5) Impossible to complete the 90-day follow-up

Design outcomes

Primary

MeasureTime frame
modified Rankin scale at 90d;

Secondary

MeasureTime frame
National Institute of Health stroke scale;Intracranial hemorrhage transformation within 7 days;Early neurological deterioration (END) within 7days;Futile recanalization at 90 days;Stroke recurrence at 90d;Death at 90d;

Countries

China

Contacts

Public ContactXu Anding

The First Affiliated Hospital of Jinan University

tlil@jnu.edu.cn+86 130 0689 1327

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026