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Clinical study of colquhounia root tablets combined with iguratimod in the treatment of rheumatoid arthritis: Study protocol for a randomized controlled trial

Clinical study of colquhounia root tablets combined with iguratimod in the treatment of rheumatoid arthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072567
Enrollment
Unknown
Registered
2023-06-16
Start date
2023-06-20
Completion date
Unknown
Last updated
2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis

Interventions

Treatment group:Colquhounia root tablets combined with iguratimod
Control group:Iguratimod

Sponsors

The First Affiliated Hospital of Henan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Those who meet the 2010 ACR/EULAR classification standards; (2) After X-ray shooting, the grade is determined to be grade I-III according to the grading standards for joint dysfunction; (3) The patient gave informed consent to this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Heart, liver, kidney dysfunction or joint lesions that may be caused by cardiovascular and cerebrovascular diseases; (2) Pregnant women, lactating women and women with fertility needs during treatment; (3) Persons with mental illness or those who have taken drugs for mental illness in the near future; (4) Patients with allergies and those who are allergic to the drugs used in this study; (5) Active peptic ulcer/bleeding, or previous recurrent ulceration/bleeding; (6) Bone marrow hematopoietic disorders, severe anemia, low white blood cells, platelets.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale, erythrocyte sedimentation rate, c-reactive protein, Disease Activity Score 28;

Secondary

MeasureTime frame
Rheumatoid factor, morning stiffness time, number of tender joints, number of swollen joints, grip strength;

Countries

China

Contacts

Public ContactZihua Wang

The First Affiliated Hospital of Henan University of Chinese Medicine

wzh_010@126.com+86 188 3811 2169

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026