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Clinical efficacy evaluation and mechanism study of Qutan Huoxue Fang in the treatment of metabolic related fatty liver disease

Clinical efficacy evaluation and mechanism study of Qutan Huoxue Fang in the treatment of metabolic related fatty liver disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072550
Enrollment
Unknown
Registered
2023-06-16
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolically associated fatty liver disease

Interventions

Qutan Huoxue formula granule group:Gynostemma pentaphylla 20g, White art 12g, turmeric 9g, Rhodiola rosea 6g, raw Hawthorn 15g
Qutan Huoxue formula simulates granules:10% Qutan Huoxue Fang granules, 90% maltodextrin

Sponsors

Ningbo Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Those who meet the above diagnostic criteria of Chinese and Western medicine; 2. Aged 18-65 years; 3.ALT greater than the upper limit of normal value (male > 50IU/L, female > 40 IU/L), and less than or equal to 5 times the upper limit of normal value; 4. Sign patient informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who add other liver protection and enzyme lowering drugs in the past 3 months and affect the efficacy evaluation; 2. Alcoholic fatty liver disease (alcohol intake > 20g/d for men and > 10g/d for women), cirrhosis, hepatitis B, hepatitis C and other liver diseases, autoimmune liver disease or taking some drugs that may cause fatty liver disease; 3. Patients with normal liver function; 4. Patients who have had gastrointestinal bariatric surgery in the last year or who have taken weight-loss drugs in the last 3 months have lost more than 10% of their body weight; 5. Age > 65, or < 18; 6. Pregnant and lactating women, primary diseases of cardiovascular, lung, kidney, hematopoietic system and other serious diseases such as malignant tumors.

Design outcomes

Primary

MeasureTime frame
ALT;MRI-PDFF;

Secondary

MeasureTime frame
Abdominal Fibroscan CAP value;AST;weight;the waist;

Countries

China

Contacts

Public ContactLi Hongshan

The Second Hospital of Ningbo

lihongshan_1982@126.com+86 137 3886 5021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026