lower extremity arteriosclerosis obliteration
Conditions
Interventions
Treatment Group:Sichong tablet+Aspirin/Clopidogrel+ Rosuvastatin
Control Group:Aspirin/Clopidogrel+ Rosuvastatin
Sponsors
Jinan Municipal Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients diagnosed with lower limb arteriosclerosis obliterans (Rutherford stage 1) and voluntarily participating in the study by signing an informed consent form, aged between 18-75 years old.
Exclusion criteria
Exclusion criteria: (1) Patients who have had allergic reactions or adverse reactions to tetrahydropyranyl-tetrahydofurfuryl-naphthoic acid or other experimental drugs; (2) Patients with blood disorders such as coagulation dysfunction, anemia, platelet abnormalities, etc.; (3) Patients with bleeding disorders within the last 3 months; (4) Patients at high risk of major bleeding due to digestive ulcers, malignant tumors, esophageal varices, arteriovenous malformations, vascular aneurysms, etc.; (5) Patients with serious complications such as heart, brain, lung diseases, liver or kidney dysfunction; (6) Patients with inflammatory vascular diseases such as thromboangiitis obliterans, large-vessel vasculitis, or Raynaud's syndrome; (7) Pregnant and lactating women; (8) Patients with mental disorders; (9) Patients who are estimated by the investigator to have poor compliance and may have difficulty cooperating with treatment; (10) Patients with incomplete medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ankle brachial pressure index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood lipid level;Skin temperature;Arterial blood flow parameters of lower limbs;The expression levels of TNF-a, IL-1ß, NF-?B p65, and I?Ba in peripheral blood; | — |
Countries
China
Contacts
Public ContactWANG Yutao
Jinan Municipal Hospital of Traditional Chinese Medicine
Outcome results
None listed