postoperative pulmonary infection
Conditions
Interventions
Dexmedetomidine atomizing group (DEX group):Aerosol inhalation of dexmedetomidine
Normal saline spray control group (NS group):Normal saline control
Sponsors
The Second Affiliated Hospital of Wannan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 120 patients with emergency craniocerebral trauma were selected; 2. Underwent craniotomy and hematoma removal under general anesthesia; 3. The patients aged 18~65 years, ASA grade II-IV.
Exclusion criteria
Exclusion criteria: 1. Preoperative patients with pulmonary infection, pulmonary bulles, pneumothorax, chronic obstructive pulmonary disease and other severe respiratory diseases, implantable pumps such as pacemakers and automatic implantable defibrillators, and severe cardiovascular diseases were excluded from the study; 2. Preoperative chest CT showed atelectasis. 3.Severe disease of liver and kidney function. 4.shock.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| GI index based on pulmonary electrical impedance tomography (EIT);atelectasis;SP-A protein;Postoperative pulmonary infection; | — |
Countries
China
Contacts
Public ContactZha Jun
The Second Affiliated Hospital of Wannan Medical College
Outcome results
None listed