Tumor-associated anemia
Conditions
Interventions
Treatment group:On the basis of symptomatic support treatment, add Qizao oral liquid, 2 capsules per time, 3 times a day, for a course of 4 weeks.
placebo group:On the basis of symptomatic supportive treatment, a placebo was added, with 2 tablets per session, 3 times a day, for a course of 4 weeks.
Sponsors
Dongzhimen Hospital Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: ?Gastrointestinal tumor (esophageal cancer, gastric cancer, colorectal cancer) diagnosed by imaging, histopathology or cytology.?Conforming to the diagnosis of cancerous anemia, and with mild to moderate anemia, the Hgb is below the normal value of 80g/L.?According to the "Guidelines for Clinical Research on the Treatment of Qi and Blood Deficiency Syndrome with New Chinese Medicines and the Clinical Research Guidelines for the Treatment of Blood Deficiency Syndrome with New Chinese Medicines" issued by the Drug Administration of the Ministry of Health of the People's Republic of China, the diagnostic criteria are as follows: short breath, lazy speech, limb fatigue, dizziness, palpitations, insomnia, and a dull complexion; Tongue pulse: The tongue is pale, the coating is thin and white, and the pulse condition is heavy and weak. Having 3 symptoms, combined with tongue pulse diagnosis of "Qi and blood deficiency syndrome".?Age 18 and above.?KPS score above 70 points.?Expected survival time>3 months.?One month before enrollment, Chinese and Western medicines for anemia were not used.?No chemotherapy regimen was used before enrollment, or chemotherapy regimen was discontinued for at least one month ( washout period ).?Voluntary subjects, signed informed consent.
Exclusion criteria
Exclusion criteria: ?Does not meet the inclusion criteria above?.Accompanied by heart, liver, kidney and other important organ dysfunction.?Pregnant women and mental patients.?Not according to the provisions of medication.?Due to severe toxic side effects during treatment, treatment was forced to be interrupted.?Patients diagnosed with blood diseases such as aplastic anemia and myelodysplastic syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hgb;RBC;HCT;MCV;RDW;MCHC;WBC;LYM;MONO;GRA;PLT;PCT;MPV;platelet distribution width, PDWC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Short of breath and lazy speech;Light-headedness;Palpitation and insomnia;Colorless face;Physical fatigue;Karnofsky; | — |
Countries
China
Contacts
Public ContactLu Yang
Dongzhimen Hospital Beijing University of Chinese Medicine
Outcome results
None listed