Inguinal hernia
Conditions
Interventions
Control Group:Opioid drugs are used to anesthesia induce and maintain
Esketamine Group:Esketamine is used to anesthesia induce and maintain
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. ASA grade I-III; 3. Patients undergoing elective laparoscopic herniorrhaphy;
Exclusion criteria
Exclusion criteria: 1. Incarcerated hernia or recurrent hernia; 2. Cognitive impairment or difficulty in communication; 3. Severe circulatory andrespiratory diseases such as severe coronary heart disease and COPD; 4. Endocrine diseases such as pituitary adenomas, severe diabetes, cortisol syndrome, pheochromocytoma, etc.; 5. Mental and psychological diseases: such as schizophrenia, depression, history of chronic analgesics, alcoholism, opioid dependence; 6. Patient refused to participate in this study; 7. Allergy to esketamine; 8. Body mass index > 30 kg/m^2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of quality of recovery-15 scale (QoR-15) scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of QoR-15 scale;Numerical Rating Scale (NRS) pain score;Incidence of adverse events such as dyspnea, hypoxemia (SPO2 < 95%), nausea and vomiting in postanesthesia care unit;Postanesthesia care unit stay time;Consumption of analgesics;Time of first reporting of pain;Time of first request for pain relief;Adverse reaction;Hospitalization time;Hospitalization expenses;Sleep quality ; | — |
Countries
China
Contacts
Public ContactChen Lijian
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed