emergence agitation
Conditions
Interventions
dexmedetomidine group:20 min before the end of surgery, 0.2ug/kg dexmedetomidine was injected intravenously
remimazolam group:20 min before the end of surgery, 0.2mg/kg remimazolam was injected intravenously
Sponsors
Tongji Hospital affiliated to Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: Pediatric patients aged 2-12 years, ASA grade I.-II., and undergoing elective tonsillectomy and/or adenoidectomy were selected.
Exclusion criteria
Exclusion criteria: (1) Patients younger than 2 years old or older than 12 years old; (2) ASA classification =III.; (3) hypersensitivity to dexmedetomidine or remazolam; (4) Preoperative pulmonary dysfunction (including pneumonia, acute lung injury, acute respiratory distress syndrome, etc.); (5) preoperative cardiac dysfunction; (6) Preoperative liver and kidney dysfunction; (7) Have a history of mental illness; (8) Patients with developmental delay and neurological disorders; (9) Patients who have participated in other studies within 90 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time after intervention; the length of stay in PACU ;the peak of PAED scores;the incidence of PONV;Parental satisfaction; | — |
Countries
China
Contacts
Public ContactLuo Fang
Tongji Hospital affiliated to Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed