sepsis
Conditions
Interventions
heparin group:N/A
no-heparin group:N/A
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients admitted to ICU: (1) age =18 years; (2) met the definition of sepsis 3.0 criteria, which was defined as suspected infection combined with an acute increase in sequential organ failure assessment (SOFA) score of =2. (3) The worst SIC-related score within 24 hours after ICU admission was SIC =4.
Exclusion criteria
Exclusion criteria: (1) multiple ICU admissions; (2) age < 18 years, length of ICU stay < 24h; (3) heparin for dialysis or treatment rather than prophylaxis; Low molecular weight heparin or warfarin was given during ICU stay. (4) pregnant women; (5) history of embolism and thrombosis; (6) history of heparin thrombocytopenia; (7) liver failure; (8) chronic kidney disease, stage 5; (9) Malignant tumors. (Disease based ICD9 or ICD10)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| mechanical ventilation;AKI; | — |
Countries
China
Contacts
Public Contactzhiye zou
Guohui Nie
Outcome results
None listed