Labor analgesia
Conditions
Interventions
sufentanil control group:Measure the EC50 of sufentanil in non obese pregnant women under the condition of 0.1% Ropivacaine
sufentanil obesity group:Measure the EC50 of sufentanil in obese pregnant women under the condition of 0.1% Ropivacaine
Ropivacaine control group:Measured the EC50 of Ropivacaine in non obese pregnant women under the condition of 0.5 µg/ml sufentanil
Ropivacaine obesity group:Measured the EC50 of Ropivacaine in obese pregnant women under the condition of 0.5 µg/ml sufentanil
Sponsors
Department of Anesthesiology, the Second Affiliated Hospital of Suzhou University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Natural primiparous women aged 20-40 years, single pregnancy 37-42 weeks; 2. Height 155-175 cm; 3. No history of miscarriage; 4. Require epidural analgesia and uterine dilation = 7.
Exclusion criteria
Exclusion criteria: 1. Contraindication of epidural anesthesia; 2. Premature rupture of membranes; 3. Complications of heart, lung, kidney, and/or liver diseases; 4. Complications of severe preeclampsia or malignant tumors; 5. History of lower abdominal surgery; 6. A medical history of long-term use of sedatives or painkillers; 7. History of mental illness; 8. Other conditions not suitable for Vaginal delivery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of labor;Hemodynamic;Apgar score;Cord blood gas analysis;Parturient women satisfaction;patient-controlled epiduralanalgesia (PCEA) press times and effective times;Total dosage of analgesic pump;Duration of pain relief;additional dosage times;Maternity's overall VAS score for the delivery process;delivery outcome; | — |
Countries
China
Contacts
Public ContactZhu Jiang
The Second Affiliated Hospital of Soochow University
Outcome results
None listed