Gestational Diabetes Mellitus(GDM)
Conditions
Interventions
GDM group:N/A
Normal pregnancy group:N/A
Sponsors
Department of Obstetrics and Gynecology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medcine
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Signed informed consent form with date commitment Comply with the study procedures and cooperate with the whole process of the study Women with the age between 18 and 45 years old Women were healthy at the first antenatal examination Women without cardiovascular disease, rheumatic immune disease or diabetes before this pregnancy; without multiple pregnancy, assisted birth conception or coagulation disorder; without VTE family or personal history, previous recurrent spontaneous abortion hisrory or smoking history Cooperate with all the examination of this study
Exclusion criteria
Exclusion criteria: Women who have miscarriage during pregnancy, go to another hospital for delivery, get treatment with other investigational agents during the study period, have diagnosed coagulopathy and rheumatic immunity diseases, cardiovascular diseases, malignant tumors and other diseases in the prenatal examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VTE risk score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin resistance index;Fibrinogen;D-dimer;CRP;IL-6;protein C;protein S;antithrombin III;platelet counts;E-Selectin;vascular cell adhesion molecule-1, VCAM-1; intercellular adhesion molecule-1,CAM-1;Lower limb venous flow velocity;fasting glucose;fasting insulin ;BMI; | — |
Countries
China
Contacts
Public ContactWeiwei Feng
Department of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medcine
Outcome results
None listed