Cochlear Implantation/Cognitive Decline
Conditions
Interventions
Cochlear implantation candidate group:None
Previously implanted cochlear implant group:None
Normal control group:None
Sponsors
Sun Yat-sen Memorial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Selection criteria for cochlear implantation candidates: 1. Aged greater than 18 years; 2. Post-lingual deafness; 3. Severe to profound deafness on at least one side, meeting the indications for cochlear implantation. Selection criteria for previous cochlear implant participants: 1. Aged greater than 18 years; 2. Post-lingual deafness; 3. At least one-year post-cochlear implant surgery. Selection criteria for normal control participants: 1. Aged greater than 18 years; 2. Average hearing threshold less than 40dB at 0.5, 1, 2, and 4kHz in both ears.
Exclusion criteria
Exclusion criteria: Cochlear implantation candidacy exclusion criteria: 1. Patients with congenital hearing loss, language disorders, and visual impairments; 2. Patients with mental illnesses; 3. Clinically diagnosed dementia patients. Previous cochlear implant recipient exclusion criteria: 1. Patients with congenital hearing loss, language disorders, and visual impairments; 2. Patients with mental illnesses; 3. Clinically diagnosed dementia patients. Normal control exclusion criteria: 1. Patients with language disorders, and visual impairments; 2. Patients with mental illnesses; 3. Clinically diagnosed dementia patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shape trial test (STT);Resting state near-infrared imaging;Shape trial test task state near-infrared imaging;Nijmegen Cochlear Implant Questionnaire;BKBSIN (BKB speech in noise);Mandarin version of AzBio Sentence Test;Shape trial test (STT);Resting state near-infrared imaging;Shape trial test task state near-infrared imaging;Nijmegen Cochlear Implant Questionnaire;BKBSIN (BKB speech in noise);Mandarin version of AzBio Sentence Test;Shape trial test (STT);verbal influency task (VFT);Resting state near-infrared imaging;Shape trial test task state near-infrared imaging.;Nijmegen Cochlear Implant Questionnaire;BKBSIN (BKB speech in noise);Mandarin version of AzBio Sentence Test;Shape trial test (STT);Resting state near-infrared imaging;Resting-state EEG (electroencephalography);Shape trial test task state near-infrared imaging.;Nijmegen Cochlear Implant Questionnaire;BKBSIN (BKB speech in noise);Mandarin version of AzBio Sentence Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Population baseline characteristics collection;Mini-mental State Examination (MMSE);verbal influency task (VFT);Resting-state EEG (electroencephalography);spectral-temporally modulated ripple test;Mini-mental State Examination (MMSE);verbal influency task (VFT);Resting-state EEG (electroencephalography);spectral-temporally modulated ripple test;Mini-mental State Examination (MMSE);Resting-state EEG (electroencephalography);Spectral-Temporally Modulated Ripple Test;Mini-mental State Examination (MMSE);verbal influency task (VFT);Spectral-Temporally Modulated Ripple Test; | — |
Countries
China
Contacts
Public ContactHaidi Yang
Sun Yat-sen Memorial Hospital
Outcome results
None listed