Breast cancer
Conditions
Interventions
P group:Receive ultrasound-guided thoracic paravertebral block,preformed at T4-5 with 25 ml of 0.4% ropivacaine
E group:Remifentanil combined with intravenous and inhalation general anesthesia for pain relief
Sponsors
Sun Yat-sen University, Cancer Center
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: a) Proposed breast cancer surgery under general anesthesia b) Age 18-80 years old c) ASA I-II grade d) Volunteers who sign informed consent and can complete the recovery quality scale e) Have not participated in other clinical drug trials within the last three months
Exclusion criteria
Exclusion criteria: a) Contraindications to paravertebral block (such as coagulation dysfunction or infection and trauma at the block site) b) Allergy to the drug of the study c) History of preoperative opioid use d) Long-term use of alcohol or psychotropic drugs e) factors that may increase the risk of participating in treatment or that may interfere the results of the trial and patients are considered unsuitable for inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR15 score at 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR15 score at 48 hours after surgery;VAS scores at rest and activity at 24 and 48 hours after surgery;Supplemental analgesic drug dosage after 24 and 48 hours after surgery;Adverse reactions (e.g., nausea, vomiting, headache and dizziness); Patient satisfaction; | — |
Countries
China
Contacts
Public ContactLai Renchun
Sun Yat-sen University, Cancer Center
Outcome results
None listed