Infectious diseases of the lower respiratory tract
Conditions
Interventions
Experimental group:=6 months ~ <2 years old: 1ml of ambroxol hydrochloride solution for inhalation, inhalation, 2 times a day
=2 years old ~ =12 years old: 2ml of ambroxol hydrochloride solution for inhalation, inhalation, 2 times a day
Control group:=6 months ~ <2 years old: 1ml of ambroxol hydrochloride solution matrix for inhalation, inhalation, 2 times a day
= 2 years old ~ = 12 years old: 2ml of ambroxol hydrochloride solution matrix for inhalation, inhalation, 2 times a day.
Medication time: 2 doses every 24 hours, with no less than 6 hours between 2 do
Sponsors
Beijing Children's Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
0.5 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for lower respiratory tract infections (such as acute bronchitis, pneumonia, etc.); 2. Must have sticky sputum and difficulty coughing up sputum (cough =2 points) symptoms; 3. Hospitalized children; 4. Age 6 months to 12 years old, gender is not limited; 5. Voluntary signing of consent form by the legal guardian of the admitted child (at the same time> 10aged children need to voluntarily sign the informed consent form)
Exclusion criteria
Exclusion criteria: 1. Those with allergies (those who are allergic to more than two types of substances) or those who are known to be allergic to the ingredients contained in the experimental drugs; 2. Children with upper respiratory tract infection; 3. Children with lower respiratory tract infection with wheezing symptoms (need bronchodilator therapy); 4. Children with severe pneumonia, bronchiolitis, bronchial asthma, bronchiectasis and pulmonary fibrosis; 5. Those with respiratory depression or tissue hypoxia; 6. Patients with serious cardiovascular and cerebrovascular, liver, kidney and hematopoietic system primary diseases; 7. Patients with drug dependence, or patients with mental disorders; 8. Those who have participated in or are participating in other clinical trials within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| Phlegm in the larynx;Pulmonary rales; | — |
Countries
China
Contacts
Public ContactKunling Shen
Beijing Children's Hospital Affiliated to Capital Medical University
Outcome results
None listed