Complex alveolar bone defects
Conditions
Interventions
Experimental group :guided bone tissue regeneration
Control group:external autogenous bone
Sponsors
The Third Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1: Patients aged 18 to 60 years old, of any gender 2: Patients with complex alveolar bone defects, including: 1) Terheyden bone defect classification 3/4 type - horizontal and vertical bone defects. 2) Terheyden bone defect classification 4/4 type - vertical bone defects 3: The missing tooth has been absent for at least 3 months 4: Patients with good general health, as evaluated by the researcher, and able to tolerate surgery 5: Patients with good oral health 6: Patients who voluntarily sign an informed consent form 7: Patients who are compliant, willing to receive treatment, and able to actively cooperate with the treatment.
Exclusion criteria
Exclusion criteria: 1: Patients who refuse to sign the informed consent form 2: Patients with untreated or unhealed periodontal disease or other oral diseases that the researcher considers may affect the treatment effect 3: Patients with obvious local or systemic severe infections 4: Patients with severe cardiovascular diseases 5: Patients with severe allergic constitution that the researcher considers unsuitable for participation in this study 6: Patients with poorly controlled diabetes 7: Patients with uncontrolled systemic diseases such as hypertension 8: Patients who smoke heavily (more than 10 cigarettes per day) 9: Patients with a history of radiation or chemotherapy 10: Patients currently participating in other clinical trials or who have completed clinical trials but have not reached six weeks 11: Patients who are mentally incapable or unable to understand the requirements of participating in the study 12: Breastfeeding, pregnant women or those who have plans to become pregnant in the near future 13: Patients with poor compliance who are unwilling to cooperate with the follow-up of each stage 14: atients that the researcher considers unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Actual bone gain at 24 weeks postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complication rate;Immediate surgical success rate; | — |
Countries
China
Contacts
Public ContactWei Ma
The Third Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed