Insomnia
Conditions
Interventions
Chronic insomnia group 1:Conventional drug therapy
Chronic insomnia group 2:oxygen therapy + Conventional drug therapy
Depression comorbid insomnia group 1:Conventional drug therapy
Depression comorbid insomnia group 2:Oxygen therapy + Conventional drug therapy
Generalized anxiety disorder comorbid insomnia group 1:Conventional drug therapy
Generalized anxiety disorder comorbid insomnia group 2:Oxygen therapy + Conventional drug therapy
Health control group:None
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients with chronic insomnia (n1=60) ?Meet the diagnostic criteria for chronic insomnia in ICSD-3; ?Age between 18 and 65 years old; ?Chinese, Han nationality; ?Understand the research content and sign the informed consent form. (2) Major depressive disorder comorbid with insomnia (n2=60) ?Meet the diagnostic criteria for chronic insomnia in ICSD-3 and major depressive disorder in DSM-V; ?Age between 18 and 65 years old; ?Chinese, Han nationality; ?Understand the research content and sign the informed consent form. (3) Patients with generalized anxiety disorder and insomnia (n3=60) ?Meet the diagnostic criteria for chronic insomnia in ICSD-3 and generalized anxiety disorder in DSM-V; ?Age between 18 and 65 years old; ?Chinese, Han nationality; ?Understand the research content and sign the informed consent form. (4) Healthy control group (n0=30) Inclusion criteria: ?No sleep disturbance and mental illness; ?Age between 18 and 65 years old; ?Chinese, Han nationality; ?Understand the research content and sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? There are serious physical diseases that affect this study; ? Comorbidity with other mental disorders (such as schizophrenia, post-traumatic stress disorder, etc.); ? Comorbidity with other sleep disorders (such as sleep apnea syndrome (AHI>15 ), sleep-related movement disorders (PLMS index > 15); ? alcohol, drug and other substance abuse in the past year; ? obvious suicidal ideation or suicide attempt or Hamilton Depression Scale 24 suicide item score = 2; ? visual acuity or It is difficult to cooperate with the completion of the study with corrected vision; ?Cannot communicate normally due to language and other problems; ?Participated in or is currently participating in clinical trials related to this study within 3 months; ?Cannot cooperate with researchers due to various other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Event-related potential;Polysomnogram; | — |
Countries
China
Contacts
Public ContactLiwen Tan
The Second Xiangya Hospital of Central South University
Outcome results
None listed